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Last medically reviewed/updated: Dr. Shruti Bhattacharya, March 19, 2026 Anxiety feels physical when your chest tightens like a band, your heart races for no clear reason, or fatigue settles into your bones even after sleep. These sensations are real. In the US, an estimated 19.1% of adults experience any anxiety disorder in a given year, with women at 23.4% and men at 14.3%. While globally hundreds of millions carry these loads, and in India about 11 in 100 people face mental health challenges, the body’s whispers feel just as personal everywhere. Recent insights show that immune activity can quietly shape…